Nanomol
    Technologies

  • The company
  • Successful cases
  • R+D
  • Clients
  • News
  • Contact

    Particle
    technologies

  • Delos enabled products
  • Benefits and advantages
  • Partnering
  • Delos nanovesicles
  • Solid particulate materials

    Contract
    analysis

  • Services
  • Analysis
  • Quality
  • Expertise and equipment
Back to the gallery

News

New nanocarrier for bio-imaging and drug-delivery applications
24 January 2020

New nanocarrier for bio-imaging and drug-delivery applications

An article titled "MKC-Quatsomes: a stable nanovesicle platform for bio-imaging and drug-delivery applications" has been published online in Nanomedicine: Nanotechnology, Biology and Medicine journal. The new nanovesicle formulation is based on the quatsome architecture - which stands out due to the high colloidal stability and homogeneity in size – and has now been shown to be suitable for in vivo dosing.  

In collaboration with the Oncogenesis and Antitumour Drug group of the Biomedical Research Institute of the Hospital de la Santa Creu i Sant Pau, led by Dr. Ramon Mangues, MKC-Quatsomes were tested in live mice bearing xenografted colorectal tumors. After intravenous injection of fluorescently labelled MKC-Quatsomes, biodistribution assays showed nanovesicle accumulation in tumors, liver, spleen, and kidneys, but not in any other organ. Importantly, MKC-Quatsomes were well-tolerated at the administered doses, and no histological alterations or toxicity was found in any of these organs. These new results suggest the applicability of quatsomes in therapeutic approaches that require systemic delivery. 

The article has been authored by researchers from Institut de Ciència de Materials de Barcelona (ICMAB-CSIC), Biomedical Research Institute Sant Pau and Josep Carreras Research Institute, Facultat de Farmàcia i Ciències de l'Alimentació de la Universitat de Barcelona, Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN) and Nanomol Technologies SL.

Article of reference:

MKC-Quatsomes. A stable nanovesicle platform for bio-imaging and drug-delivery applications co-authored by Guillem Vargas-Nadal et al., Nanomedicine: Nanotechnology, Biology and Medicine, 24 (2020) 102136. 

https://doi.org/10.1016/j.nano.2019.102136

 

 

Related
news

Nanomol has participated in II International Congress Bioprocesses Cuba 2019 18 June 2019

Nanomol has participated in II International Congress Bioprocesses Cuba 2019

Nanomol Technologies is hiring a Process Engineer! 27 December 2022

Nanomol Technologies is hiring a Process Engineer!

Nanomol Technologies are going to participate in Farmaforum 2020 03 March 2020

Nanomol Technologies are going to participate in Farmaforum 2020

come and visit us

NANOMOL TECHNOLOGIES, S.L.
Mòdul de Recerca B
UAB CAMPUS

08193 Bellaterra
Cerdanyola del Vallès
Barcelona
Spain

get in touch

T +34 935 868 963
INFO@NANOMOL-TECH.COM

follow us

Twitter Linkedin

terms of use

Privacy policy Legality

Copyright © 2023

Nanomol Technologies S.L.

Site by Suki

This website uses cookies.